ATP synthase is a well conserved multimeric protein All

ATP synthase is a well conserved multimeric protein. All organisms studied to date contain homologs of 8 different subunits which are essential for the complexes function. However, you have just completed sequencing the genome of a novel organism, which despite having a functional ATP synthase, it only has genes which are homologous to 5 of the 8 essential subunits. On the basis of these findings you hypothesise that the ATP synthase of the novel organism contains novel subunits which fulfil the same functional role as the missing essential subunits. Describe, a series of experiments you could perform to identify the novel subunits and the genes that code for them.

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