Offspring Parents Normal CFNS Family number Father Mother Male Female Male Female normal CFNS normal CFNS 5 2 normal CFNS normal CFNS CFNS normal 2 8. 10a 3 2 normal CFNS CFNS normal 10b 2 12 13a normal CFNS 2 13b CFNS normal 0. 2 7b CFNS normal 2 O NO1010
Craniofrontonasal syndrome (CFNS) is a birth defect in which premature fusion of the cranial sutures leads to abnormal head shape, widely spaced eyes, nasal clefts, and various other skeletal abnormalities. George Feldman and his colleagues looked at several families in which offspring had CFNS and recorded the results shown in the following table (G. J. Feldman. 1997. Human Molecular Genetics 6:1937–1941).
Q. On the basis of these results, what is the most likely mode of inheritance for CFNS?
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